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Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates

10.1038/s42255-022-00591-z 51 NelsonG.WordsworthJ.WangC.JurkD.LawlessC.Martin-RuizC.et al (2012)

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The increase of tert-butyl hydroperoxide-initiated chemiluminescence is indicative that -tocopherol is the antioxidant consumed in erythrocytes and suggest that reactive oxygen species and lipid peroxidation catalyzed by reduced transition metals may be responsible for the onset of oxidative damage and the occurrence of systemic oxidative stress in patients suffering oxidative damage associated to neurological pathologies as Parkinson (Famulari et al., 1996, Dominguez et al., 2008), Alzheimer disease (Famulari et al., 1996

Standard L-Glutathione may require conversion in the body, potentially reducing efficacy

[DOI] [PubMed] [Google Scholar] **5.Glew RH, Sun Y, Horowitz BL, et al