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Many clinicians actively recommend PPI therapy for semaglutide users with significant reflux symptoms

These findings suggest that these lipid profiles may serve as potential biomarkers for distinguishing patients with atypical depressive features (91, 92)

The carcinogenic risk of GLP-1RAs remains controversial: large-scale cohort studies have not identified an association with pancreatic cancer 36 , but animal experiments suggest that long-term high-dose use may induce ductal hyperplasia 37,38

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Activated Wnt/-catenin signalling enhanced net DAergic neurogenesis in parkinsonian rats by regulating pro-neural genes (Nurr-1, Pitx-3, Ngn-2, and NeuroD1) and mitochondrial biogenesis