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Severe Gastrointestinal Disease (e.g., Gastroparesis): Consult a healthcare provider

The 1 mg dose has direct human diabetes-trial activity. Below 1 mg is more speculative

Most people get enough vitamin B12 in a protein-rich diet that includes meat, poultry, eggs, dairy products, and fortified foods such as breakfast cereal

DOI Sikiric P, et al

However, it's important to note that comprehensive human clinical trials remain limited, and most safety and efficacy data comes from animal studies

A few, because of these frightening experiences, have ended up with a condition akin to post-traumatic stress disorder (PTSD)