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Retrieved 27 May 2026

Central and peripheral molecular targets for antiobesity pharmacotherapy. Clinical pharmacology and therapeutics vol

However, the recovery of these regenerative capabilities (by increased expression of NAMPT for example) change the physiology of the cells towards stem-like cells, gaining some cancer properties, such as unlimited proliferative capacity, altered metabolism, DNA-repair, methylation alterations, with phenotype similar to CSCs, which deregulation by any other mutation initiate the tumor