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Patients with OA exhibit elevated iron levels in synovial tissue, and the impairment of iron homeostasis-regulating genes causes cellular iron accumulation, resulting in heightened production of ROS as well as the increased level of collagen II and MMP13, which are established hallmarks of OA [85] (Figure 2)
Current Biology : CB, 26(24), R1260
There are a total of 27 claudins in mammals, although not all claudins have relevance for the intestinal barrier [19]
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An accredited outside lab (ISO 17025) carries far more weight than an unnamed in-house bench checking itself
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