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Results showed dose-dependent weight loss: the 0.25mg dose produced 4.5% additional weight loss beyond diet and placebo, the 0.5mg dose achieved 9.2% weight loss, and the 1.0mg dose resulted in 10.6% weight lossrepresenting approximately twice the efficacy of other approved obesity drugs available at that time

In Peutz-Jeghers syndrome, pigmentation is more extensive and speckled

Challenges and Future Prospects Despite promising findings, GLP-1RAs face limitations in addiction treatment

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