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1970 Aug;45(242):445-52

Over 29 days of treatment, the peptide inhibited pulmonary artery muscularization (the thickening and stiffening of pulmonary arteries that drives this condition), prevented right heart hypertrophy (the enlargement of the right ventricle that occurs when it has to pump against increased resistance), and significantly decreased mortality

Treatment is not guaranteed, results vary, and weight regain is possible if medication is stopped without an ongoing plan

Estimated dosage per spray: 1 spray 66mcg 2 sprays 132mcg 4 sprays 264mcg 8 sprays 528mcg Because nasal absorption is generally lower than injectable administration, higher overall usage amounts are commonly discussed compared with subcutaneous use

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