We then compared free cysteine thiol levels between WT and mutant chondrocytes and observed no difference between the two genotypes during proliferation, but free cysteine thiols were increased in G6PDH-null chondrocytes compared to WT chondrocytes during differentiation, suggesting decreased oxidative protein folding (Fig
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In addition, because BPC-157 is a gastric peptide, there have been some informal reports of digestive side effects like nausea, diarrhea, appetite changes, gas and bloating related to its administration