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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023

Recognized adverse effects include cholelithiasis, gastrointestinal disturbances, and reductions in lean mass [10,11,12]

How Long Does It Take to See Weight Loss Results with GLP-1

The FDA has raised concerns about the increased risk of dosing errors, improper storage and fraudulently labeled GLP-1s from compounding pharmacies

Regular teeth cleaning can disrupt the biofilm of decay causing bacteria, especially when fluoride toothpaste is used

The defense will be able to present opposing evidence in a non-adversarial format