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For moderate hyperkalemia, urinary K excretion should be increased by administration of diuretics, such as furosemide, and sodium bicarbonate in individuals with metabolic acidosis

Thirdly, the observational design of this study, together with the absence of longitudinal molecular measurements, prevents definitive causal inference regarding selenium, brain aging, and the molecular candidates identified

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Towards this goal, molecules that are associated with pathophysiological mechanisms (for example, pathophysiological mediators altered in the disease conditions) are promising candidates for such biomarkers

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