Furness JB, Kunze WA, Clerc N
Initially, GLP-1 medication was developed to treat type 2 diabetes and, although it is effective, other significant weight loss benefits were also found , leading to their use as a weight management tool
Typical protocols use 1.6mg administered subcutaneously twice weekly for maintenance, with some practitioners using daily dosing during acute treatment phases
a c ) Representative images of TH immunofluorescence of the whole SNc/VTA brain region from Trkb Penk-WT control ( a ), Trkb Penk-KO mutant injected with Gsto2 -shRNA ( b ) or scrambled-shRNA ( c ) in the striatum at 3 M
We have a hell of a lot of these L cells in the colon as well, and honestly, nobody understands what they are doing there
In 2008, Rimonabant (also known as SR141716) was withdrawn from the market worldwide after being approved in 2006 due to serious psychiatric side effects that outweighed its benefits, including suicide