The diacid structure provides dual carboxyl groups that enhance albumin binding affinity compared to monocarboxylic fatty acids
Indeed, sequence analysis has shown that many viral (mainly glyco-) proteins are amyloidogenic, and may aggregate like A (Tetz and Tetz, 2018), while facilitating intercellular spread of misfolded protein pathology (Liu et al., 2021)
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J Histochem Cytochem (2011) 59(3):27888
Endoproteolytic cleavage of human thyroperoxidase: role of the propeptide in the protein folding process
Additional exclusion criteria included any personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 in the baseline period