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157 While corticosteroids and other immunosuppressive agents exert broad anti-inflammatory effects, direct inhibition of NLRP3 inflammasome activation represents a more specific therapeutic strategy, potentially allowing for more effective suppression of inflammation with reduced off-target effects

module genome_name bin_name contig_name db_name module_name module_class module_category module_subcategory module_definition stepwise_module_completeness pathwise_module_completeness stepwise_module_is_complete pathwise_module_is_complete module_completeness proportion_unique_enzymes_present enzymes_unique_to_module unique_enzymes_context_string enzymes_unique_to_module unique_enzymes_hit_counts enzymes_unique_to_module enzyme_hits_in_module module_definition gene_caller_ids_in_module enzyme_hits_in_module warnings module_completeness Module copy number values in the output Module copy number is always computed, so modules mode output will always include three columns describing the estimated copy number of each module: pathwise_copy_number , stepwise_copy_number , and per_step_copy_numbers (these columns are omitted for pangenome input, since copy number is not a meaningful concept there)

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Figure 1 One of the core characteristics of ferroptosis is the collapse of the antioxidant defense system