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The mechanism shown below proceeds via protonation of the carbonyl not the amide N (see step 1 )

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If youre injecting tirzepatide from a vial, pinch an inch of skin and fatty tissue between your fingers

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Monoamine reuptake modulation (Tesofensine): a small molecule originally studied in central-nervous-system research, of interest for its monoaminergic mechanism

These models exhibit abnormal mitochondrial morphology in neurons, consistent with features of ferroptosis