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Folate and vitamin B 12 are important for cell division and tissue growth through their involvement in pyrimidine and purine nucleotide synthesis for DNA and RNA, maintenance of genomic stability and methylation reactions (Reference Bailey, Stover and McNulty5Reference Allen, Miller and De Groot7)

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The freeze-dried format helps preserve product integrity during storage until prepared for laboratory use

The following sections delve into the specific roles of uremic toxins, oxidative stress, inflammation, and iron imbalance in triggering eryptosis, providing a comprehensive overview of the pathophysiological mechanisms underlying renal anemia

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This observation aligns with the rationale that RSL3 is a drug that inhibits GPX4 and thus, enhances the sensitivity of cells to ferroptosis