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Furthermore, markedly elevated activities of APX, catalase and GST in a cytokinin-overproducing tobacco line were accompanied with a significantly lower number of HR-lesions and reduced levels of TNV, as compared to wild type controls (Pogny et al., 2004)
Applying the GPX4 inhibitor RSL3 or knocking down GPX4 can enhance cell lipid peroxidation, while FSP1 overexpression attenuates RSL3-induced lipid peroxidation
Spiekerkoetter, U., Bastin, J., Gillingham, M., Morris, A., Wijburg, F., and Wilcken, B
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In contrast, the negative effects of deficiency on the mitochondrial function, cholesterol metabolism, synthesis of steroid hormones (sex hormones) and formation of carcinogenic nitrosamines are relatively well comprehended
