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The blood cultures may be negative in patients who have already received antibiotics or in patients who have IE caused by fastidious microorganisms such as petronella species, brucella species , Coxiella burnetii , bacteria in the HACEK group ( haemophilus species , actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens and Kingella kingae ), and Tropheryma whipplei

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