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Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (81821002, 81790251, 81430071, 81672381, 81972665 and 81772487), Guangdong Basic and Applied Basic Research Foundation (2019B030302012), the National 973 Basic Research Program of China (2013CB911300), the Science and Technology Department of Sichuan Province (No

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The electron energy loss spectrum, zero-loss images and energy-filtered elemental maps were acquired using an Ultrascan 4000 charge-coupled detector from Gatan

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This result highlights the value of combining cell-state-specific drugs to treat cancer