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Results Phenotypes of MC4R-deficient mice MC4R KO mice showed a significant increase in body weight, food intake, fat mass, and lean mass compared with those in normal mice

H., Bi, C., & Holick, M

(2010) reviewed L-carnitines role in primary and secondary carnitine deficiency, establishing the clinical rationale for supplementation in conditions where endogenous synthesis or dietary intake is insufficient [3]

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