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Dal Bello, G., Gisondi, P., Idolazzi, L

Folate antagonism is known to contribute to the antiproliferative effects that are important in the action of methotrexate against malignant diseases, but concomitant administration of folic or folinic acid does not diminish the anti-inflammatory potential of this agent, which suggests that other mechanisms of action might be operative

Contraindications: Use as part of a varied and balanced diet

V., Kirby, M

Studying two cohorts of CFS ( n = 10) and GWS patients ( n = 10), one pooled and the other looking at individual cases, Baraniuk found very similar CSF proteome differences relative to a healthy control group ( n = 10) (Baraniuk et al., 2015)

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