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For patients taking oral semaglutide (Rybelsus), proper administration is critical: take with no more than 4 oz (120 mL) of plain water, at least 30 minutes before the first food, beverage, or other oral medications of the day

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The once-weekly, triple-hormone receptor agonist delivered significant weight loss across doses, with the highest dose resulting in 28.3% weight loss during the 80-week period

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