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NCDs, including cardiovascular diseases, diabetes, cancers, chronic respiratory conditions, and obesity, account for 74% of global deaths

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For instance, in the pivotal SURPASS-2 trial, patients receiving the highest tirzepatide dose (15 mg) achieved a mean body weight reduction of 11.2 kg, nearly twice that observed with semaglutide 1 mg (5.7 kg) (19)

IL-33 induces antigen-specific IL-5 + T cells and promotes allergic-induced airway inflammation independent of IL-4