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At these doses, you should be working closely with your provider and monitoring for side effects

Biomedicines 10:1430

Proper training in handling these substances is essential to mitigate risks

The goal is finding the minimum effective dose, not automatically climbing to the maximum

A 2024 assessment of registered clinical trials on L-Arginine and L-Citrulline interventions for hypertension - published in the journal Pharmaceuticals - found significant heterogeneity in the existing evidence, noting that inconsistencies in study design make it difficult to precisely quantify effect size, and that not all translational studies may have influenced vascular reactivity in the same way

Additionally, increased circulation and oxygen delivery to injured or damaged areas helps with cell turnover, reducing the appearance of scars