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9 kg), reduces depression scores and improves QoL dimensions such as mood and self-image, with changes correlating with the magnitude of weight loss (138)

Actual rates of alopecia were low, ranging from roughly 3 to 9 per 1,000 people per year, with between 11,000 and 15,000 people in each drug-class group

Metabolites of this drug are known to be substantially excreted by the kidney, and the risk of toxic reactions may be greater in patients with impaired renal function