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References Vieira FT et al

In a recent article in Science, chemist Derek Lowe points out two other instances of missed opportunities: (1) the head of research at Schering-Plough, which now manufactures Claritin, once said that there arent any nonsedating antihistamines and (2) when a large pharma company decided not to develop metformin to treat type 2 diabetes

Eventually, cAMP modulation may be a way to break past plateaus experienced by many patients

Pfizer would get exclusive rights to the program and would spearhead any clinical development that came out of the work

GLP-1 analogues as adjunctive therapy for type 1 diabetes: systematic review and meta-analysis (24 RCTs, N=3,377)

Many commercial plans cover GLP-1 receptor agonists for type 2 diabetes