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Mean weight loss induced by semaglutide and tirzepatide in obese but nondiabetic individuals

Maintaining a healthy and balanced lifestyle is key to keeping weight off after semaglutide

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doi: 10.1056/NEJMoa2028395

Applying heat to the neck and shoulders for 1520 minutes, practicing progressive muscle relaxation, or using a cold compress on the forehead can relieve mild-to-moderate headaches without medication

While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine