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It directly inhibited the stearoyl-CoA desaturase-1 (SCD1) protein to trigger ferroptosis of ovarian cancer, evidenced by the increased ROS, total iron, and Fe 2+ levels and downregulation of ferroptosis inhibitors (SLC7A11 and GPX4), thus suppressing cancer progression in the SKOV-3 xenograft model (Liu et al., 2022)

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Rather than protecting heart health, as fish oil supplements are supposed to do, they can do damage: oxidized lipids have demonstrated negative effects on atherogenic lipids and other biomarkers of cardiovascular disease and may be predictive of clinical events in patients with cardiovascular risk or disease

Free Radic Biol Med 2008