The lifespans of different sterile mutants are dependent on distinct genetic pathways known to contribute to longevity We next investigated whether the genes exhibiting differential expressions in glp-1(-), fem-3(-) , and mog-3(-) mutants shared enrichment of any specific transcription factor binding motif, which would suggest putative transcriptional regulators
Long-term data from tirzepatide trials extend to 72 weeks, showing continued weight loss with minimal plateauing
In this context, there is a positive correlation between fecal SCFA concentration and IBS-symptom severity, indicating that there may be an association between metabolite production and gut microbiota (Tana et al., 2010)
Turning GLP-1 Into a Sustainable Lifestyle Tool GLP-1 medications can be life-changing, but they are most effective when paired with intentional nutrition
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Gastroenterology 168 (2), 424