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Initially prescribed to treat diabetes, these meds are becoming recognized as a miracle drug that might help with an array of ailments from heart failure to mental health to alcohol abuse

They are not competitors: they are two branches of the same tree, pruned for different purposes

Animal experiments Animal experiments were performed using hemizygous or homozygous human FcRn Tg32 mice (B6.Cg- Fcgrt tm1Dcr Tg(FCGRT)32Dcr/DcrJ, The Jackson Laboratory)

Possible mechanisms include the reduction of retinal endothelial cell apoptosis and mitigation of gradual central retinal thinning with SGLT2i, a neuroprotective role in retinal ganglion cells with GLP1-ra, as well as a reduction in the oxidative stress and vascular remodelling with both medications [12,13,14,15,16]

Journal of Tissue Engineering 15:20417314241303818

Published 2014 Oct 30