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In this study, 475 patients were randomized

To this end he began exploring leptin, a new hormone discovered in 1994 by Jeffrey Friedman, a molecular geneticist with an interest in weight regulation at Rockefeller University in New York

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For biopharma executives, this serves as a reminder of the importance of resilience and adaptability in drug development

In tandem, the arcuate nucleus of the hypothalamus, which contains both anorexigenic proopiomelanocortin-expressing neurons and orexigenic agouti-related protein/neuropeptide Y-co-expressing neurons, has a key role in the homeostatic control of food intake 4

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