(STEP-1 Trial, NEJM 2021) It happens because semaglutide slows the rate at which food leaves your stomach, which can make you feel fuller and queasier than usual
In the SURMOUNT-1 trial, adults taking injectable tirzepatide lost an average of about 15% with the 5 mg dose, 19.5% with the 10 mg dose, and 20.9% to 22.5% with the highest 15 mg dose after 72 weeks
If you are only interested in weight loss, then a regular Semaglutide plan may be right for you
When semaglutide helps someone lose weight, this may improve hormone balance
Most likely, the main risk is reduced effectiveness rather than immediate harm
Talk to your doctor about whether you need continuous glucose monitoring even without a diabetes diagnosis