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The long-acting GLP-1 agonist segment dominated the market in 2025 owing to its superior dosing convenience, improved patient observation, and sustained therapeutic efficacy

Peptides 32 , 15931599 (2011) Barwell, J., Conner, A

[1, 2] Examples of GLP-1 long-acting medicines are [1, 2]: Dulaglutide (once a week) Exenatide extended-release (once a week) Semaglutide (once a week) Oral GLP-1 Drug Most GLP-1 drugs are administered via injections, typically as subcutaneous injections

In that form, its called Zepbound

The medications, called GLP-1 receptor agonists, use a synthetic version of the natural substance to activate the hormones receptors

Common Withdrawal Symptoms Increased Appetite : Without the appetite-suppressing effects of GLP-1 medications, many individuals may find themselves feeling hungrier than before