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The upregulation of glutamate-cysteine ligase, an enzyme involved in GSH synthesis, has been observed in some thalassemia patients as a compensatory response to oxidative stress
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For purely academic research (in vitro or preclinical), this does not change the protocols, but any researcher working concurrently in a sports-related context should be aware that detection is possible
Lu C-L, Zheng C-M, Lu K-C, Liao M-T, Wu K-L, Ma M-C (2021) Indoxyl-sulfate-induced redox imbalance in chronic kidney disease
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