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2025;69(2):e2300316

With coverage Medicare Part D CV indication: cost-share depends on plan tier and benefit phase

Eisenberg D, Azagury DE, Ghiassi S, et al

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IGF-1 LR3 is hypothesized to mitigate these risks by supporting neuronal survival and improved cardiac output

To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7