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The Nrf2 pathway of SFN is essential for providing the neuroprotective advantages against several brain illnesses through multiple pathways and by activating results in enhanced expression of multiple downstream molecules, i.e., NAD(P)H quinone oxidoreductase-1 (NQO1), Heme oxygenase-1 (HO-1), Glutathione peroxidase-1 (GPx-1), and Gamma-glutamylcysteine synthetase ( -GCS), that provide defense against oxidative stress (95)

Key Features Powerful Antioxidant: Neutralizes free radicals and reactive oxygen species (ROS) to protect cells from oxidative stress

2018;10(11) Int J Mol Sci

Social Support: Strong social connections and support are effective for stress reduction

In our study, the fold change in 2MT-evoked neural activation (relative to water control) was significantly greater in the APC than in the PPC

Schlenzig JS, Charpentier C, Rabier D, et al