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The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain

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doi:10.1016/j.ejphar.2020.173368 Yilmaz H, Sahin S, Sayar N, et al

The role of Drp1 has been identified as a contributing factor in the pathogenesis of Parkinsons disease (Wu et al., 2017), with a substantial body of evidence demonstrating the involvement of -Syn, DJ-1, LRRK2, PINK1, and Parkin in the regulation of mitochondrial dynamics and homeostasis through the Drp1 pathway (Irrcher et al., 2010

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The following day, culture media was changed and cells were treated with either LPS (500 ng/mL) to stimulate an immune response in vitro or 1X dPBS as a negative control