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Approximately 39 amino acids similar in length to tirzepatide, longer than semaglutide (31 amino acids)

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Phentermine elevates heart rate and blood pressure by stimulating norepinephrine release, while semaglutide can independently affect cardiovascular functionparticularly in patients with pre-existing hypertension or cardiac risk factors

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The ratio of oxidized to reduced glutathione (GSSG/GSH ratio) is regarded as an indicator for tissue redox conditions [47,53] and it is increased at 10 to 60 min in the Aldh2*2 KI homozygous mice compared with the WT mice (Fig