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Its relevance to neuropathy is most direct in the metabolic neuropathies, particularly diabetic peripheral neuropathy, where impaired glucose metabolism, insulin resistance, and mitochondrial dysfunction all contribute to nerve damage

Sprason C, Tucker T, Clancy D (2024) MtDNA deletions and aging

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Titration Schedule After the first 4 weeks, we might up the ante to 0.5 mg weekly, depending on how were handling it