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Published in NEJM in 2022, SURMOUNT-1 randomized 2,539 adults with obesity (BMI 30) or overweight (BMI 27) with weight-related conditions, without diabetes, to tirzepatide 5mg, 10mg, 15mg, or placebo, alongside diet and exercise

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76 Additionally, excessive GSH may alter bacterial intracellular redox homeostasis, which paradoxically leads to increased production of ROS and causes oxidative damage

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That goes for name-brand or compounded medications