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Peer review Peer review information Nature Communications thanks Karen Dwyer and the other anonymous reviewer(s) for their contribution to the peer review of this work

These combined actions have led to interest in its relevance for research models involving cardiovascular stress and impaired circulation.(23) Further animal-based investigations have reported protective effects in models of cardiac injury

In the 1 mg trial arm, liver fat fell 51% among participants with fatty liver, visceral fat fell 16%, triglycerides declined, and ketones rose as the liver used more fat. Modeled metabolic-health protocols place heavier, metabolically average profiles near 1 mg weekly

doi: 10.1002/FSN3.4568 279 ZhengYMaYXiongQZhuKWengNZhuQ

Warm environments can promote bacterial and fungal growth, posing health risks upon consumption

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