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Switching between concentrations mid-protocol This happens more often than you might think

Yes, for the vast majority of people

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Elimination - Semaglutide will still be available in the circulatory system for approximately 5 to 7 weeks post the last dose or maintenance dose of 2.4 mg

The STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program, which evaluated once-weekly semaglutide 2.4 mg for weight management, demonstrated significant weight loss (approximately 15% in STEP 1) that could indirectly affect hormone levels, though testosterone was not systematically reported in these publications

it's that symptoms don't always seem severe until they have been building for a while