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Before analysis, genotyping data were filtered to remove SNPs with low minor allele frequency ( Q110%

Tirzepatide (SURPASS trials): Weight reduction: 1521% depending on dose (515mg/week) Approved for type 2 diabetes Tolerability: mild to moderate GI effects Retatrutide (Phase 2 data): Weight reduction: 1724.2% across 1236 week protocols (515mg/week) Investigational

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