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Roches dual GLP-1/GIP receptor agonist candidate achieved 22.5% weight loss after nearly a year of treatment, setting the asset up for late-stage testing and a potential challenge to Eli Lillys mega-blockbuster obesity franchise

It can be an effective rescue medication for severe diarrhea episodes, but it should not be used routinely during retatrutide treatment

doi: 10.1111/obr.12282