This indicated that the neddylation level of NEDD4 was regulated by UBE2m (Fig
Diabetic COVID-19 patients have high cellular oxidative stress, evidenced by decreased extracellular superoxide dismutase 3 levels (Kumar D.S
Glutathione is a powerful antioxidant that supports detoxification, immune health, and protection against oxidative stress
Protein S -nitrosylation, the covalent attachment of nitric oxide (NO) moiety to the reactive thiol group of a cysteine residue to form S -nitrosothiol is an important PTM for most classes of proteins ( S -nitrosylated proteins such as Bcl-2, p53, HIF-1, PTEN, and Src are involved in cell survival, angiogenesis, tumorigenesis, and response to cancer treatment ( S -nitrosylation of Bcl-2, which inhibits its ubiquitination and subsequent proteasomal degradation ( S -nitrosylation on Cys498 residue of Src kinase induces autophosphorylation, which promotes nitric oxide-mediated cell invasion and resistance to anoikis in cancer cells ( S -nitrosoglutathione promote S -nitrosylation at the Cys183 residue of extracellular signal-regulated kinase 1/2 (ERK1/2), which leads to inducing apoptosis in U251 glioma cells ( S -nitrosylation affects a variety of proteins that play important roles in the cellular dysfunctions and contribute to cancer progression and response to chemotherapy
Circ_0001093 promotes glutamine metabolism and cancer progression of esophageal squamous cell carcinoma by targeting miR-579-3p/glutaminase axis
Many chronic health conditions are associated with low glutathione levels, including autoimmune diseases and heart disease
