doi: 10.3389/fendo.2022.1033479 Received 31 August 2022 Accepted 27 October 2022 Published 17 November 2022 Volume 13 - 2022 Edited by Jianbo Zhou, Beijing Tongren Hospital, Capital Medical University, China Reviewed by Finbarr P
What to Expect: GLP-1 Side Effect Reality Check Nausea : The most frequently reported side effect, typically more prominent when first starting or increasing doses Vomiting : Less common than nausea, possible during initial adjustment Diarrhea or constipation : Can occur alongside other GI effects Reduced appetite : A therapeutic effect that helps with weight loss, but can sometimes feel uncomfortable Many patients report that side effects decrease significantly after the first few weeks, and severe reactions requiring discontinuation are relatively rare
This was not a post-hoc analysis or observational study
These supplements may reduce fermentation time, which can lead to gas and sulfur burps
Tirzepatide, which activates both GLP-1 and GIP receptors, may produce different effects compared to pure GLP-1 agonists
Eur J Pharmacol (2015) 765:4827