The cytokines IL-1, IL-6, IL-13 and IL-22 have been demonstrated to alter intestinal transcription of CLDN2 [27,28,29,30], although the impact this has on subsequent pore pathway permeability has not been fully elucidated
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In this sense, CLD is the 10th reason for mortality globally (Younossi and Henry, 2016
Acta Gastroenterol Latinoam 40 (4): 351-3
10.7150/thno.70588 70 HuangJ
GLP-1 receptor agonists such as liraglutide, semaglutide, and dulaglutide have shown significant reductions in major adverse cardiovascular events (MACE), including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke, primarily in people with established cardiovascular disease or high cardiovascular risk