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This is the practical side of the calculation that every researcher needs to consider

It operates primarily in the brainstem and spinal cord, where it acts as an inhibitory neurotransmitter

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A long-term (lifetime horizon) modelling analysis found that both liraglutide 1.2 and 1.8 mg OW were cost-effective versus dapagliflozin, with incremental cost-effectiveness ratios (ICERs) within the cost-effectiveness thresholds set by NICE in people with T2D in England and Wales [59]