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GLP-1, or glucagon-like peptide-1, is a hormone that plays a significant role in regulating appetite and glucose metabolism

Patients should understand that expected weight loss varies by medication (approximately 5-10% with liraglutide, 10-15% with semaglutide, and potentially higher with tirzepatide), though responses in post-bariatric patients may differ from those in primary obesity treatment

10.1053/j.ajkd.2024.08.002 82 TengholmA.GylfeE

Studies show GLP-1 therapy can reduce reactive oxygen species (ROS), improve mitochondrial function, lower pro-inflammatory cytokines, and enhance vascular signaling, particularly in metabolic disease [5]

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