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Its Phase 2 obesity trial published in Lancet Diabetes & Endocrinology (2024) showed up to 18.7% weight loss at 46 weeks, while a separate Phase 2 MASH trial demonstrated significant MASH resolution, earning FDA Breakthrough Therapy Designation

10.2337/dc14-2364 [DOI] [PubMed] [Google Scholar] 85.Goldenberg RM

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They found L-carnitine supplementation to significantly decrease erythropoietin resistance index (ERI) in a group of patients receiving intravenous L-carnitine