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While the clinical significance of this interaction remains uncertain because this combination compounded product has not undergone clinical trials and no specific studies have evaluated contraceptive efficacy during semaglutide therapy, caution is warranted

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When supplements are part of your routine, choosing formulations that prioritise absorption may improve consistency and tolerance

Both Retatrutide and Tirzepatide are supplied as lyophilized powders requiring reconstitution with bacteriostatic water

According to the Therapeutic Goods Administration, the drug can also cause kidney failure, shortness of breath, chest pain, abdominal cramping and dizziness

doi: 10.1038/s41568-023-00628-9